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A resident in the Dande HDSS is defined as: any person who lives, has been living or intends to stay in a household for a period of at least 3 months; or infants born to residents.

The centre is a collaboration between the Angolan Ministry of Health, the Portuguese Institute of Language and Development and Calouste Gulbenkian Foundation.

The first HDSS was implemented in 1940 in South Africa.

There are now around 50 known HDSS worldwide, with surveyed population ranging between 13 350 and 260 000 individuals; 39 sites are spread in Africa, none of them in Central Africa or closest to Angola.

Man made irrigation channels are used for several purposes, namely drinking water, personal hygiene and washing clothes and dishes, which increases the risk for water-related diseases such as urogenital Schistosomiasis, a prevalent disease in the studied area.

The HDSS area is served by 10 primary health care facilities, two health centres, one maternal and infant health centre, one municipal hospital and one general hospital.

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